Special edition: Prion diseases

Special Edition: Editorial

It is surprising that over 60 years have elapsed since the first use of influenza vaccines, yet with the advances in biotechnology that have occurred in the interim, the majority of the influenza vaccines that we use today are still non-living viral antigens produced in a relatively uncontrolled substrate, the embryonated chicken egg. It is also surprising that the impact of seasonal influenza ...

MJM Special Abstract Edition

Investigation of positional and orientational contributions to visual shape integration in amblyopic patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .93 Richard Dallala, Robert Hess, Behzad Mansouri, Yi-Zhong Wang Nrf2 and Cul3 are potential biomarkers for the evaluation of chemoresistant breast cancer . . . . ...

Special 45th Anniversary Edition

Prion Diseases

Stanley Prusiner introduced the term prion (proteinaceous infectious particle) and proposed that the infectious agent in prion diseases is composed mainly or entirely of an abnormal conformation of an otherwise normal host-encoded glycoprotein called the prion protein (PrP)1. This hypothesis was initially greeted with great skepticism in the scientific community but then later was widely acknow...

Infectious Diseases, 3d Edition